Donate

 

 
ForumForumDiscussionsDiscussionsDrugs, healthca...Drugs, healthca...Imipramine and Methylphenidate Hydrochloride (Ritalin)Imipramine and Methylphenidate Hydrochloride (Ritalin)
Previous Previous
 
Next Next
New Post
 03/04/2012 15:05
 
 Modified By Caroline  on 03/04/2012 20:05:45

Has anyone had problems with this comination of drugs? My son is currently on 45mg of the MH and 20 mg of Imip, (he is 6yrs old) since he has been on the Imip we have noticed that he is napping more and the angery has returned with a vengence, we are also bacxk to having the slightist thing upsets him and then turns into a major issue. Although Josh is starting to show some more personality than he had when he was on MH and Clomiprine we are starting to feel we have taken major steps backwards. Josh's cataplexy is also still really bad and if anything seems to be getting worse with the slightist thing making him fall to the ground.

I know when I read the leaflet for the Imip that one of the side effects was that it could interferre with MH but to this extent?

Can anyone give me some advice on how to go and whether it is worth carry on with this cominbation.

Thanks

New Post
 03/04/2012 16:54
 

Hello Caroline

It might help if you change the title of your question as most people would recognise Ritalin/Concerta/Mediknet or Equasymn before they did methylphenidate?

I am so sorry that Josh is going through this again and I am sorry to say I can't provied any direct answers. I hope the following might help you and anyone who has the same problems.

Imipramine is something known as a tricylic antidepressant and is given to people with narcolepsy not because they are depressed but because it helps to control several of the side effects of the disease. It used to be said that imipramine should not be used on children under 7 because of the side effects though I note that the BMJ now say under 6. Ritalin (methylphenidate) should be given with imipramine with care as the two drugs inter react and the ritalin can increase the levels of imipramine in the blood, which is probably why Josh is on such a low dose (and his age of course).

All the literature I have read suggests that the two drugs are not a long term solution as Raynal et all back in the 1970's discovered that people with narcolepsy can quickly build up a tolerance to Ritalin, with six months not being unusual - but then again with this blasted condition neither is 20 years. That was for those people who have been on it for 20 years and have not had a problem. Classic side effects of the drugs are weight gain, sexual side effects and changes in personality.

So, and remember I am not a doctor, I would guess that Josh is starting to become used to the Ritalin and because of that it isn't having the same effect on him or on his imipramine.

Please anyone else out there had similar problems and how did you solve it?

New Post
 03/04/2012 20:07
 

Thanks John,

I have included Ritalin in the title. Am seeing Josh's consultant on the 17th so hopefully he can suggest something, although on past form he will probably ask me what I want to do and what I think is best!

New Post
 08/04/2012 08:24
 

We were encourished to have brakes with medikinet on holidays etc. to avoid body to build tolerance. She is almost 9 years now, and so far had been able to go to school with the help of this drug. With these young ones I think the dose should be as small as possible. Some risks are accepted when life is not worth living without the risk of drugs. Decisions are somethimes frustratingly difficult.

Some kids here are hospitalised to psyciatric units and parents are losing custody rigths and braking apart. So lets do everything before it is too late.

New Post
 30/05/2012 09:20
 

This story of children in psych units because of narcolepsy was something I had not heard before. We raised it with Markku Partinen at the Edinburgh meeting and he said that yes, in Finland two children had been sent to secure units, short term as they had anger issues and were a danger to themselves and their family. However in his view this had nothing to do with medication and people should not worry that it has. In fact in both cases medication helped the issue and the children were only in hospital for short times.

Previous Previous
 
Next Next
ForumForumDiscussionsDiscussionsDrugs, healthca...Drugs, healthca...Imipramine and Methylphenidate Hydrochloride (Ritalin)Imipramine and Methylphenidate Hydrochloride (Ritalin)

Forum terms & conditions: please read before using the forum
Minimize
The views on the online community do not represent those of Narcolepsy UK. To provide the best possible service, we keep an active interest in the topics being discussed, while making sure that the forum remains strictly for your discussions.

Your Content must:

  • be accurate where it states facts
  • be genuinely held where it states opinions
  • comply with applicable law in any country in which they are posted.

Your Content must not:

  • contain any material which is defamatory of any other person or organisation
  • contain any material which is obscene, racist, sexist or offensive in any way
  • engage in bullying on the site
  • infringe any copyright, database right or trade mark of any other person
  • be likely to deceive
  • be made in breach of any legal duty owed to a third party such as a contractual duty or a duty of confidence
  • be used as an advertisement or to promote a survey
  • be likely to disrupt our service in any way
  • give the impression that they emanate from us where this is not the case
  • advocate, promote or assist any unlawful act such as (by way of example only) copyright infringement or computer misuse.
     
Common sense & disclosure of personal information

Please use caution and common sense when using the Site. Keep your password secure and contact us if you think it might be used by someone else. We cannot guarantee in any way that other registered users of the forum are who they say they are, are always honest and acting in good faith. Any registered users who we feel might be abusing the spirit of the forum and who fail to comply with the terms and conditions above could have the privilege of using the site removed from them.

Content on this site is monitored on a daily basis. If you read a post that you find breaks any of the above regulations, press the report post button and that post will be flagged up to a moderator. We reserve the right to reject, block, suspend or remove content at any time and at our sole discretion. We in no way guarantee that your content will be displayed on the Site.

Always exercise caution on the site. Do not disclose your full name or have your user name as your full name. Do not give details of your phone numbers, email address, home address or of your workplace to any person.
 

Indemnity

You agree to compensate the charity and our respective directors, officers, employees, and applicable third parties in full from and against all third party claims, liabilities, losses and expenses (including reasonable legal fees) suffered by such persons arising out of, or related to or which may arise from Your Content and/or any breach by you of any term of this Agreement.



 

Privacy Statement   |  Terms Of Use
Copyright 2010 Narcolepsy UK (Charity Registration No: 1144342 Scottish Charity No SC043576)